UM-171

DB19449InvestigationalSmall molecule

UM-171 is a pyrimidoindole derivative that is an agonist of ex vivo hematopoietic stem cell expansion and thus supports the expansion of hematopoietic stem cells.

Chemical structure of UM-171
Formula / weight
C25H27N9 · 453.554 g/mol (avg)
Code names
UM-171

Resolves to

Compound
UNII8XZ4J0KS9CCAS1448724-09-1ChEMBLCHEMBL4535214
Structure
InChIKeyAZXXGVPWWKWGAE-IYARVYRRSA-NSMILESCN1N=NC(=N1)C1=CC2=C(C=C1)C1=C(N2)N=C(CC2=CC=CC=C2)N=C1N[C@H]1CC[C@H](N)CC1
Targets
P11309PIM1

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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6Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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