Imarikiren

DB19464InvestigationalSmall molecule

Imarikiren is a small molecule drug. The usage of the INN stem '-kiren' in the name indicates that Imarikiren is a renin inhibitor. Imarikiren has a monoisotopic molecular weight of...

Mechanism: Pharmacologically active on Renin
Curator reviewed
Formula / weight: C₂₇H₄₁N₅O₄ · 499.656 g/mol (avg)
Code names: TAK-272 FREE BASE

Resolves to

Compound

UNII01IC75R817CAS1202265-63-1ChEMBLCHEMBL3990145ChEBI756530PubChem44554894

Structure

InChIKeyRHIBAIKQWJNESW-YADHBBJMSA-NSMILESCOCCCCN1C(=NC2=CC=CC=C12)C(=O)N(CC(C)C)[C@@H]1CNC[C@@H](C1)C(=O)N1CCOCC1

Targets

P00797REN

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Imarikiren, and which of those have an active Phase 3 trial?

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