Ponalrestat

DB19717ExperimentalSmall molecule

Ponalrestat is a small molecule drug. The usage of the INN stem '-restat' in the name indicates that Ponalrestat is a aldose reductase inhibitor. Ponalrestat has a monoisotopic molecular weight...

Formula / weight: C₁₇H₁₂BrFN₂O₃ · 391.196 g/mol (avg)
Code names: ICI-128436

Resolves to

Compound

UNII2CV0A5G64ECAS72702-95-5ChEMBLCHEMBL7679ChEBI93199PubChem5278

Structure

InChIKeyLKBFFDOJUKLQNY-UHFFFAOYSA-NSMILESOC(=O)CC1=NN(CC2=C(F)C=C(Br)C=C2)C(=O)C2=CC=CC=C12

Targets

Q9NY91SLC5A4P15121AKR1B1

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ponalrestat, and which of those have an active Phase 3 trial?

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