Gemilukast

DB19882InvestigationalSmall molecule

Gemilukast is a small molecule drug. The usage of the INN stem '-lukast' in the name indicates that Gemilukast is a leukotriene receptor antagonist. Gemilukast is under investigation in clinical... Gemilukast is under investigation in clinical trial NCT01536041 (A Placebo and Active Controlled Study of ONO-6950 in Asthmatic Patients).

Mechanism: Pharmacologically active on Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene receptor 1
Curator reviewed
Formula / weight: C₃₆H₃₇F₂NO₅ · 601.691 g/mol (avg)
Code names: ONO-6950

Resolves to

Compound

UNII42I6GGX6D6CAS1232861-58-3ChEMBLCHEMBL3597634ChEBI755651PubChem46830962

Structure

InChIKeySILHYVDKGHXGBL-UHFFFAOYSA-NSMILESCC1=C(CCCC(O)=O)C2=C(F)C=CC(C#CC3=CC=C(OCCCCC4=C(C)C(F)=CC=C4)C=C3)=C2N1CCCC(O)=O

Targets

Q9NS75CYSLTR2Q9Y271CYSLTR1

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Gemilukast, and which of those have an active Phase 3 trial?

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