Cysteinyl leukotriene receptor 1

BE0000705ProteinHumansCYSLTR1

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. It is acted on by 16 drugs in DrugBank.

Gene name
CYSLTR1
UniProtKB entry
Q9Y271Swiss-Prot
Cellular location
Cell membrane
Residues / weight
337 residues · 38,541 Da
Also known as
CYSLT1 · CysLTR1 · Cysteinyl leukotriene D4 receptor · G protein-coupled receptor HG55 · HMTMF81

Resolves to

Protein
UniProtQ9Y271UniProt nameCLTR1_HUMAN
Gene
HGNCHGNC:17451NCBI Gene10800GenBank5353887GeneCardsCYSLTR1
Pharmacology
IUPHAR/GtoPdb269KEGGhsa:10800
Structure
PDB6RZ4PDB6RZ5
Drugs

What you can answer from here — as of September 07, 2019

16DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
91+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cysteinyl leukotriene receptor 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In