Bimakalim

DB19948ExperimentalSmall molecule

Bimakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Bimakalim is a potassium channel activator, antihypertensive. Bimakalim has a monoisotopic molecular...

Mechanism: Pharmacologically active on ATP-binding cassette sub-family C member 9, ATP-sensitive inward rectifier potassium channel 11, and ATP-sensitive potassium channel
Curator reviewed
Formula / weight: C₁₇H₁₄N₂O₂ · 278.311 g/mol (avg)

Resolves to

Compound

UNII4MP5GR4H9LCAS117545-11-6ChEMBLCHEMBL12552

Structure

InChIKeyJTVSKASWNROQQF-UHFFFAOYSA-NSMILESCC1(C)OC2=C(C=C(C=C2)C#N)C(=C1)N1C=CC=CC1=O

Targets

O60706ABCC9Q14654KCNJ11

What you can answer from here — as of September 16, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bimakalim, and which of those have an active Phase 3 trial?

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