Lapretolimod

DB20120InvestigationalSmall molecule

Lapretolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Lapretolimod is a toll-like receptor (TLR) agonist. Lapretolimod is under investigation in... Lapretolimod is under investigation in clinical trial NCT03799510 (Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children).

Mechanism: Pharmacologically active on Toll-like receptor 4
Curator reviewed
Formula / weight: C₉₆H₁₈₁N₂O₂₂P · 1746.47 g/mol (avg)

Resolves to

Compound

UNII6CY69F2AH3CAS960324-04-3ChEMBLCHEMBL5394901

Structure

InChIKeyJSNQJZJCKAFSHT-OPYGSFAOSA-NSMILES

CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@H]1[C@H](OC[C@H]2O[C@H](O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]2O)O[C@H](CO)[C@@H](OP(O)(O)=O)[C@@H]1OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

Targets

O00206TLR4

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Lapretolimod, and which of those have an active Phase 3 trial?

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