Donitriptan

DB20163ExperimentalSmall molecule

Donitriptan is a small molecule drug. The usage of the INN stem '-triptan' in the name indicates that Donitriptan is a sumatriptan derivative serotonin (5HT1) receptor agonist. Donitriptan has a... Donitriptan has a monoisotopic molecular weight of 403.2 Da.

Mechanism: Pharmacologically active on 5-hydroxytryptamine receptor 1B, Prostaglandin D2 receptor 2, and 5-hydroxytryptamine receptor 1D
Curator reviewed
Formula / weight: C₂₃H₂₅N₅O₂ · 403.486 g/mol (avg)

Resolves to

Compound

UNII70968BVH2JCAS170912-52-4ChEMBLCHEMBL1742428ChEBI750025PubChem197706

Structure

InChIKeySOHCKWZVTCTQBG-UHFFFAOYSA-NSMILESNCCC1=CNC2=CC=C(OCC(=O)N3CCN(CC3)C3=CC=C(C=C3)C#N)C=C12

Targets

P28222HTR1BQ9Y5Y4PTGDR2P28221HTR1D

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Donitriptan, and which of those have an active Phase 3 trial?

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