5-hydroxytryptamine receptor 1B

BE0000797ProteinHumansHTR1B

G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1315531, PubMed:1328844, PubMed:1348246, PubMed:1351684, PubMed:1559993, PubMed:1565658, PubMed:1610347, PubMed:23519210, PubMed:23519215, PubMed:29925951, PubMed:8218242). It is acted on by 48 drugs in DrugBank.

Gene name
HTR1B
UniProtKB entry
P28222Swiss-Prot
Cellular location
Cell membrane
Residues / weight
390 residues · 43,568 Da
Also known as
5-HT-1B · 5-HT-1D-beta · 5-HT1B · HTR1DB · S12

Resolves to

Protein
UniProtP28222UniProt name5HT1B_HUMAN
Gene
HGNCHGNC:5287NCBI Gene3351GenBank219679GeneCardsHTR1B
Pharmacology
IUPHAR/GtoPdb2KEGGhsa:3351
Structure
PDB4IAQPDB4IARPDB5V54
Drugs

What you can answer from here — as of September 07, 2019

48DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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194+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 1B, how selective are they, and which programs against it are still in active trials?

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