Metrifudil

DB20226ExperimentalSmall molecule

Metrifudil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Metrifudil is a vasodilator. Metrifudil has a monoisotopic molecular weight of 371.16...

Formula / weight: C₁₈H₂₁N₅O₄ · 371.397 g/mol (avg)
Code names: TH-322

Resolves to

Compound

UNII7K4GKQ4XSECAS23707-33-7ChEMBLCHEMBL331382

Structure

InChIKeyOOEMZCZWZXHBKW-SCFUHWHPSA-NSMILESCC1=C(CNC2=C3N=CN([C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)C3=NC=N2)C=CC=C1

Targets

P0DMS8ADORA3P29274ADORA2AP30542ADORA1

What you can answer from here — as of September 13, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Metrifudil, and which of those have an active Phase 3 trial?

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