Goxalapladib

DB20736ExperimentalSmall molecule

Goxalapladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Goxalapladib is a phospholipase A2 inhibitor. Goxalapladib has a monoisotopic molecular weight...

Formula / weight: C₄₀H₃₉F₅N₄O₃ · 718.769 g/mol (avg)

Resolves to

Compound

UNIIGNG9ZD197LCAS412950-27-7ChEMBLCHEMBL2107344ChEBI752579PubChem11686305

Structure

InChIKeyOBJKLVFDRLAGJI-UHFFFAOYSA-NSMILESCOCCN1CCC(CC1)N(CC1=CC=C(C=C1)C1=CC=C(C=C1)C(F)(F)F)C(=O)CN1C(CCC2=CC=CC(F)=C2F)=CC(=O)C2=CC=CN=C12

Targets

Q13093PLA2G7

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Goxalapladib, and which of those have an active Phase 3 trial?

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