Nebentan

DB20812ExperimentalSmall molecule

Nebentan is a small molecule drug. The usage of the INN stem '-entan' in the name indicates that Nebentan is a endothelin receptor antagonist. Nebentan has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on Endothelin-1 receptor
Curator reviewed
Formula / weight: C₂₄H₂₁N₅O₅S · 491.52 g/mol (avg)
Code names: HE-11

Resolves to

Compound

UNIIIJ670B0H4ACAS403604-85-3ChEMBLCHEMBL2107760

Structure

InChIKeyLONWRQOYFPYMQD-DTQAZKPQSA-NSMILESCOC1=C(OC2=C(NS(=O)(=O)\C=C\C3=CC=CC=C3)N=C(N=C2OC)C2=NC=CC=N2)C=CC=C1

Targets

P25101EDNRA

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nebentan, and which of those have an active Phase 3 trial?

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