Endothelin-1 receptor

BE0000521ProteinHumansEDNRA

Receptor for endothelin-1. It is acted on by 23 drugs in DrugBank.

Gene name
EDNRA
UniProtKB entry
P25101Swiss-Prot
Cellular location
Cell membrane
Residues / weight
427 residues · 48,722 Da
Also known as
Endothelin receptor type A · ET-A · ETA · ETA-R · ETRA

Resolves to

Protein
UniProtP25101UniProt nameEDNRA_HUMAN
Gene
HGNCHGNC:3179NCBI Gene1909GenBank238636GeneCardsEDNRA
Pharmacology
IUPHAR/GtoPdb219KEGGhsa:1909
Structure
PDB8HCQPDB8XVIPDB8XVJ
Drugs

What you can answer from here — as of September 07, 2019

23DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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57GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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131+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Endothelin-1 receptor, how selective are they, and which programs against it are still in active trials?

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