| DB00559 | Bosentan | approved, investigational | yes | antagonist | Details |
| DB04883 | Darusentan | investigational | unknown | | Details |
| DB12548 | Sparsentan | approved, investigational | yes | antagonist | Details |
| DB05290 | SPP 301 | investigational | unknown | | Details |
| DB05367 | Actelion-1 | investigational | unknown | | Details |
| DB06403 | Ambrisentan | approved, investigational | yes | antagonist | Details |
| DB06199 | Atrasentan | investigational | unknown | | Details |
| DB06558 | Tezosentan | investigational | unknown | | Details |
| DB04674 | 2-HYDROXY-3,5-DIIODOBENZOIC ACID | experimental | unknown | | Details |
| DB06268 | Sitaxentan | approved, investigational, withdrawn | yes | antagonist | Details |
| DB08932 | Macitentan | approved | yes | antagonist | Details |
| DB00945 | Acetylsalicylic acid | approved, vet_approved | unknown | inhibitor | Details |
| DB06677 | Clazosentan | investigational | unknown | | Details |
| DB06460 | Enrasentan | investigational | unknown | | Details |