Sembragiline

DB20857ExperimentalSmall molecule

Sembragiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Sembragiline is a monoamine oxydase (MAO)-inhibitor type B. Sembragiline has a monoisotopic...

Mechanism: Pharmacologically active on Amine oxidase [flavin-containing] B
Curator reviewed
Formula / weight: C₁₉H₁₉FN₂O₃ · 342.37 g/mol (avg)
Code names: RG-1577

Resolves to

Compound

UNIIK3W9672PNJCAS676479-06-4ChEMBLCHEMBL3707394ChEBI755847PubChem10246762

Structure

InChIKeyVMAVCCUQTALHOB-INIZCTEOSA-NSMILESCC(=O)N[C@@H]1CN(C(=O)C1)C1=CC=C(OCC2=CC(F)=CC=C2)C=C1

Targets

P27338MAOB

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Sembragiline, and which of those have an active Phase 3 trial?

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