Ersentilide

DB20887ExperimentalSmall molecule

Ersentilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Ersentilide is a sematilide derivative class III antiarrhythmic. Ersentilide has a monoisotopic...

Mechanism: Pharmacologically active on Voltage-gated inwardly rectifying potassium channel KCNH2 and Beta-1 adrenergic receptor
Curator reviewed
Formula / weight: C₂₁H₂₆N₄O₅S · 446.52 g/mol (avg)
Code names: CK-3579 · HE-93

Resolves to

Compound

UNIIL2JY6Z298SCAS125279-79-0ChEMBLCHEMBL1193886

Structure

InChIKeyQZWUQVSQIFFFKY-IBGZPJMESA-NSMILESCS(=O)(=O)NC1=CC=C(OC[C@@H](O)CNCCOC2=CC=C(C=C2)N2C=CN=C2)C=C1

Targets

Q12809KCNH2P08588ADRB1

What you can answer from here — as of September 16, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ersentilide, and which of those have an active Phase 3 trial?

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