Felezonexor

DB21067InvestigationalSmall molecule

Felezonexor is a small molecule drug. The usage of the INN stem '-nexor' in the name indicates that Felezonexor is a nuclear export inhibitor. Felezonexor is under investigation in clinical... Felezonexor is under investigation in clinical trial NCT02667873 (A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors).

Chemical structure of Felezonexor
Formula / weight
C18H21ClF3N3O3 · 419.83 g/mol (avg)
Code names
CBS-9106 · S-03747 · SL-801

Resolves to

Compound
UNIIPAW9EP9BXOCAS1076235-04-5ChEMBLCHEMBL5074055
Structure
InChIKeyCMASLSTVVOYJQY-UHFFFAOYSA-NSMILESCC1=C(COCCC(C)(C)C)C(=O)N(NC2=CC=C(C(Cl)=N2)C(F)(F)F)C1=O
Targets
O14980XPO1

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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