Lonapalene

DB21339ExperimentalSmall molecule

Lonapalene is a small molecule drug. Lonapalene has a monoisotopic molecular weight of 338.06 Da.

Mechanism: Pharmacologically active on Polyunsaturated fatty acid 5-lipoxygenase
Curator reviewed
Formula / weight: C₁₆H₁₅ClO₆ · 338.74 g/mol (avg)
Code names: RS-43179

Resolves to

Compound

Structure

InChIKeyIFWMVQUGSGWCRP-UHFFFAOYSA-NSMILESCOC1=C(OC(C)=O)C2=CC=C(Cl)C=C2C(OC(C)=O)=C1OC

Targets

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Lonapalene, and which of those have an active Phase 3 trial?

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