Mevociclib

DB21454InvestigationalSmall molecule

Mevociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor. Mevociclib is under investigation in... Mevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors).

Chemical structure of Mevociclib
Formula / weight
C31H35ClN8O2 · 587.13 g/mol (avg)
Code names
SY-1365

Resolves to

Compound
UNII704LW082GICAS1816989-16-8ChEMBLCHEMBL4582951ChEBI230486PubChem118426108
Structure
InChIKeySCJNYBYSTCRPAO-LXBQGUBHSA-NSMILESCN(C)C\C=C\C(=O)NC1=CC=C(N=C1)C(=O)N[C@@]1(C)CCC[C@H](C1)NC1=NC(C2=CNC3=CC=CC=C23)=C(Cl)C=N1
Targets
P50613CDK7

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Mevociclib, and which of those have an active Phase 3 trial?

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