Orludodstat

DB21498InvestigationalSmall molecule

Orludodstat is a small molecule drug. The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor. Orludodstat is under investigation in... Orludodstat is under investigation in clinical trial NCT03404726 (A Study to Investigate BAY2402234, a Dihydroorotate Dehydrogenase (DHODH) Inhibitor, in Myeloid Malignancies).

Chemical structure of Orludodstat
Formula / weight
C21H18ClF5N4O4 · 520.84 g/mol (avg)
Code names
BAY-2402234

Resolves to

Compound
UNIIX8GF945GMKCAS2225819-06-5ChEMBLCHEMBL5077508
Structure
InChIKeyKNVJMHHAXCPZHF-JTQLQIEISA-NSMILESCCN1C(CO)=NN(C1=O)C1=C(F)C=C(C(=O)NC2=C(F)C=CC=C2Cl)C(O[C@@H](C)C(F)(F)F)=C1
Targets
Q02127DHODH

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
2Clinical trialsPhase, status and sponsor resolved per trial
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which drugs share a target with Orludodstat, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In