Bofutrelvir

DB21501ExperimentalSmall molecule

Bofutrelvir is a small molecule drug. The usage of the INN stem '-trelvir' in the name indicates that Bofutrelvir is a antiviral 3CL protease inhibitor. Bofutrelvir has a monoisotopic molecular...

Mechanism: Pharmacologically active on Replicase polyprotein 1ab
Curator reviewed
Formula / weight: C₂₅H₃₂N₄O₄ · 452.555 g/mol (avg)
Code names: MPI-10

Resolves to

Compound

UNIIT5UX5SKK2SCAS2103278-86-8ChEMBLCHEMBL4796938ChEBI152560

Structure

InChIKeyHPKJGHVHQWJOOT-ZJOUEHCJSA-NSMILESO=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)C1=CC2=CC=CC=C2N1

Targets

P0DTD1rep

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Bofutrelvir, and which of those have an active Phase 3 trial?

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