Nivasorexant

DB21506ExperimentalSmall molecule

Nivasorexant is a small molecule drug. The usage of the INN stem '-orexant' in the name indicates that Nivasorexant is a orexin receptor antagonist. Nivasorexant has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on Orexin/Hypocretin receptor type 1
Curator reviewed
Formula / weight: C₂₃H₂₃N₇O₂ · 429.484 g/mol (avg)

Resolves to

Compound

UNII0N15II81VXCAS1435480-40-2ChEMBLCHEMBL3892369

Structure

InChIKeyGKPHAIOJCHBZCT-HXUWFJFHSA-NSMILESCC1=CC(N2N=CC=N2)=C(C=C1)C(=O)N1CCOC[C@H]1CC1=CC(=CC=C1)N1N=CC=N1

Targets

O43613HCRTR1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nivasorexant, and which of those have an active Phase 3 trial?

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