Evixapodlin

DB21520InvestigationalSmall molecule

Evixapodlin is a small molecule drug. Evixapodlin is under investigation in clinical trial NCT04049617 (Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced... Evixapodlin has a monoisotopic molecular weight of 690.22 Da.

Chemical structure of Evixapodlin
Formula / weight
C34H36Cl2N8O4 · 691.61 g/mol (avg)
Code names
GS-4224

Resolves to

Compound
UNIILJ1WH7GQ72CAS2374856-75-2ChEMBLCHEMBL5095237ChEBI758814PubChem139415912
Structure
InChIKeyOIIOPWHTJZYKIL-PMACEKPBSA-NSMILESCOC1=C(CNC[C@@H]2CCC(=O)N2)N=CC(=N1)C1=CC=CC(=C1Cl)C1=CC=CC(=C1Cl)C1=NC(OC)=C(CNC[C@@H]2CCC(=O)N2)N=C1
Targets
Q9NZQ7CD274

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Evixapodlin, and which of those have an active Phase 3 trial?

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