Selnoflast

DB21522InvestigationalSmall molecule

Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor. Selnoflast is under investigation in... Selnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic Parkinson's Disease.).

Chemical structure of Selnoflast
Formula / weight
C20H29N3O3S · 391.53 g/mol (avg)
Code names
RO-7486967

Resolves to

Compound
UNIIT23RPA8WA2CAS2260969-36-4ChEMBLCHEMBL5095423ChEBI758985PubChem137402358
Structure
InChIKeyOHIFQOUPTWBQLE-UHFFFAOYSA-NSMILESCCN1CCC(CC1)S(=O)(=O)NC(=O)NC1=C2CCCC2=CC2=C1CCC2
Targets
Q96P20NLRP3

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Selnoflast, and which of those have an active Phase 3 trial?

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