Safimaltib

DB21528InvestigationalSmall molecule

Safimaltib is a small molecule drug. Safimaltib is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring). Safimaltib has a monoisotopic molecular...

Mechanism: Pharmacologically active on Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Curator reviewed
Formula / weight: C₂₀H₁₁F₆N₅O₂ · 467.331 g/mol (avg)
Code names: JNJ-67856633

Resolves to

Compound

UNIIL9790S42AICAS2230273-76-2ChEMBLCHEMBL5095244

Structure

InChIKeyAPWRZPQBPCAXFP-UHFFFAOYSA-NSMILESFC(F)(F)C1=C(C=NN1C1=C2C=CNC(=O)C2=CC=C1)C(=O)NC1=CC(=NC=C1)C(F)(F)F

Targets

Q9UDY8MALT1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Safimaltib, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account