Motugivatrep

DB21546ExperimentalSmall molecule

Motugivatrep is a small molecule drug. The usage of the INN stem '-vatrep' in the name indicates that Motugivatrep is a transient receptor potential vanilloid (TRPV) antagonist. Motugivatrep has a... Motugivatrep has a monoisotopic molecular weight of 403.14 Da.

Mechanism: Pharmacologically active on Transient receptor potential cation channel subfamily V member 1
Curator reviewed
Formula / weight: C₂₂H₂₀F₃NO₃ · 403.401 g/mol (avg)

Resolves to

Compound

UNII7SHP2FH6HQCAS920332-28-1ChEMBLCHEMBL5095073ChEBI758657PubChem137350798

Structure

InChIKeyMAWBBYZCTDJMDD-HFQYIWAZSA-NSMILESO[C@@H]1CCC2=C(C1)C(NC(=O)\C=C1/CCOC3=CC(=CC=C13)C(F)(F)F)=CC=C2

Targets

Q8NER1TRPV1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Motugivatrep, and which of those have an active Phase 3 trial?

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