Pilavapadin

DB21552InvestigationalSmall molecule

Pilavapadin is a small molecule drug. Pilavapadin is under investigation in clinical trial NCT06203002 (A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)). Pilavapadin has a monoisotopic molecular...

Mechanism: Pharmacologically active on AP2-associated protein kinase 1
Curator reviewed
Formula / weight: C₁₉H₂₃F₄N₃O · 385.407 g/mol (avg)
Code names: AAK1-IN-1 · BMS-986176 · LX-9211

Resolves to

Compound

UNII9G4RLM5X6ZCAS1815613-42-3ChEMBLCHEMBL5089410ChEBI758606PubChem118419773

Structure

InChIKeyRKAHOQATMSONTM-IBGZPJMESA-NSMILESCC(C)C[C@](C)(N)COC1=CC=C(N=C1C(F)F)C1=CC(=NC=C1)C(F)F

Targets

Q2M2I8AAK1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pilavapadin, and which of those have an active Phase 3 trial?

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