Nelutroctiv

DB21554InvestigationalSmall molecule

Nelutroctiv is a small molecule drug. Nelutroctiv is under investigation in clinical trial NCT05662215 (A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants). Nelutroctiv has a... Nelutroctiv has a monoisotopic molecular weight of 543.13 Da.

Mechanism: Pharmacologically active on Troponin I, cardiac muscle
Curator reviewed
Formula / weight: C₂₄H₂₂F₅N₃O₄S · 543.51 g/mol (avg)
Code names: AMG-594 · CK-136 · CK-3828136

Resolves to

Compound

UNII9PN6C05CTDCAS2299177-09-4ChEMBLCHEMBL5314433

Structure

InChIKeyBDIJXTIDFAIBQF-OOCUOIDPSA-NSMILES[H][C@]12C[C@@]1([H])N([C@H](C2)C(=O)N[C@H](C1CC1)C1=C(F)C=C(C(F)=C1)C(F)(F)F)C(=O)C1=CN=CC(=C1)S(C)(=O)=O

Targets

P19429TNNI3

What you can answer from here — as of September 21, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nelutroctiv, and which of those have an active Phase 3 trial?

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