Tunodafil

DB21576InvestigationalSmall molecule

Tunodafil is a small molecule drug. The usage of the INN stem '-afil' in the name indicates that Tunodafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. Tunodafil is... Tunodafil is under investigation in clinical trial NCT05976503 (A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol).

Mechanism: Pharmacologically active on cGMP-specific 3',5'-cyclic phosphodiesterase
Curator reviewed
Formula / weight: C₂₄H₃₃N₅O₄S · 487.62 g/mol (avg)

Resolves to

Compound

UNIIL9U6QT7F76CAS804518-63-6ChEMBLCHEMBL5314444

Structure

InChIKeyRXMDFMQMRASWOG-UHFFFAOYSA-NSMILESCCCN1C=C(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(CC)CC1

Targets

O76074PDE5A

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Tunodafil, and which of those have an active Phase 3 trial?

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