Gridegalutamide

DB21593InvestigationalSmall molecule

Gridegalutamide is a small molecule drug. The usage of the INN stem '-lutamide' in the name indicates that Gridegalutamide is a non-steroid antiandrogen. Gridegalutamide is under investigation in clinical trial... Gridegalutamide is under investigation in clinical trial NCT04428788 (Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer).

Mechanism: Pharmacologically active on Androgen receptor
Curator reviewed
Formula / weight: C₄₁H₄₅F₃N₈O₅S · 818.92 g/mol (avg)
Code names: BMS-986409 · CC1080412 · CC-1083611 · CC94676 · CC-94676, (3R)- · CEL-010355

Resolves to

Compound

UNIIVA228VR2DICAS2446929-86-6ChEMBLCHEMBL6068413ChEBI760325PubChem153513643

Structure

InChIKeyYUVGVJYLOFTILT-INJOXJOKSA-NSMILES

CCC1=C(OCCN2CCN(CC(=O)NC3=CC(N[C@@H]4CCC(=O)NC4=O)=CC=C3)[C@H](C)C2)C=CC(=C1)N1C(=S)N(C(=O)C1(C)C)C1=CC(=C(C=C1)C#N)C(F)(F)F

Targets

P10275AR

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Gridegalutamide, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account