Tamuzimod

DB21621InvestigationalSmall molecule

Tamuzimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Tamuzimod is a immunomodulator, both stimulant/suppressive and stimulant. Tamuzimod is under investigation... Tamuzimod is under investigation in clinical trial NCT05156125 (VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis).

Mechanism: Pharmacologically active on Sphingosine 1-phosphate receptor 1
Curator reviewed
Formula / weight: C₂₁H₁₃Cl₃F₃N₅O₃ · 546.71 g/mol (avg)
Code names: OPL-002 · VTX-002

Resolves to

Compound

UNIIK02SHW3KV9CAS2097854-81-2ChEMBLCHEMBL5314488ChEBI759193PubChem129143185

Structure

InChIKeyHNRWGYDMTRPLCQ-SNVBAGLBSA-NSMILESFC(F)(F)C1=CN2C=C(N=C2C(Cl)=C1)C1=NC(=NO1)C1=CC(Cl)=C(O[C@@H]2CCC(=O)NC2)C=C1Cl

Targets

P21453S1PR1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Tamuzimod, and which of those have an active Phase 3 trial?

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