Merigolix

DB21628ExperimentalSmall molecule

Merigolix is a small molecule drug. The usage of the INN stem '-golix' in the name indicates that Merigolix is a gonadotropin releasing hormone (GnRH) antagonist. Merigolix has a monoisotopic...

Mechanism: Pharmacologically active on Gonadotropin-releasing hormone receptor
Curator reviewed
Formula / weight: C₃₆H₃₅F₇N₄O₆ · 752.687 g/mol (avg)

Resolves to

Compound

UNIIRS62JYV9LXCAS1454272-94-6ChEMBLCHEMBL5314469ChEBI759175PubChem71727383

Structure

InChIKeyLJPSGSMPGVITHK-MHZLTWQESA-NSMILESOC(=O)CCCN[C@@H](CN1C(=O)N(CC2=C(C=CC=C2F)C(F)(F)F)C2=C(C1=O)C1(CCN(CC3=CC=C(O3)C(F)(F)F)CC1)OC2)C1=CC=CC=C1

Targets

P30968GNRHR

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Merigolix, and which of those have an active Phase 3 trial?

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