Imdatifan

DB21643ExperimentalSmall molecule

Imdatifan is a small molecule drug. The usage of the INN stem '-tifan' in the name indicates that Imdatifan is a hypoxia inducible factor (HIF)-2alpha (HIF-2a) inhibitor. Imdatifan has a... Imdatifan has a monoisotopic molecular weight of 385.05 Da.

Mechanism: Pharmacologically active on Endothelial PAS domain-containing protein 1
Curator reviewed
Formula / weight: C₁₈H₉F₆NO₂ · 385.265 g/mol (avg)

Resolves to

Compound

UNIIBL9SLT39J6CAS2511247-29-1ChEMBLCHEMBL5314521ChEBI759225PubChem155214362

Structure

InChIKeyZIEZRTWLAIDXDH-BLLLJJGKSA-NSMILESO[C@]12C[C@H](F)C3=C1C(=CC=C3OC1=CC(=CC(F)=C1)C#N)C(F)(F)C2(F)F

Targets

Q99814EPAS1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Imdatifan, and which of those have an active Phase 3 trial?

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