Icovamenib

DB21669InvestigationalSmall molecule

Icovamenib is a small molecule drug. The usage of the INN stem '-menib' in the name indicates that Icovamenib is a menin interaction inhibitor. Icovamenib is under investigation in clinical... Icovamenib is under investigation in clinical trial NCT06152042 (Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus).

Mechanism: Pharmacologically active on Menin
Curator reviewed
Formula / weight: C₃₁H₃₄N₈O₃ · 566.666 g/mol (avg)
Code names: BMF-219

Resolves to

Compound

UNII2Z737MY35ACAS2448172-22-1ChEMBLCHEMBL6068392ChEBI760305PubChem154988914

Structure

InChIKeyCPRLHPSXWZTPMC-XMMPIXPASA-NSMILESC=CC(=O)N[C@@H]1CCCN(CC2=CC(=NC=C2)C(=O)NC2=CC=C(C=C2)C2=CC3=C(N=CN=C3N2)N2CCOCC2)C1

Targets

O00255MEN1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Icovamenib, and which of those have an active Phase 3 trial?

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