Mosperafenib

DB21673ExperimentalSmall molecule

Mosperafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Mosperafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. Mosperafenib has a... Mosperafenib has a monoisotopic molecular weight of 461.1 Da.

Mechanism: Pharmacologically active on Serine/threonine-protein kinase B-raf
Curator reviewed
Formula / weight: C₂₀H₁₇F₂N₅O₄S · 461.44 g/mol (avg)

Resolves to

Compound

UNII47HG5BT4PACAS2649372-20-1ChEMBLCHEMBL6068061ChEBI759979PubChem156473463

Structure

InChIKeyZUXPFTYMSHPRQX-GFCCVEGCSA-NSMILESCN1C=NC2=CC=C(OC3=C(F)C=CC(NS(=O)(=O)N4CC[C@@H](F)C4)=C3C#N)C=C2C1=O

Targets

P15056BRAF

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Mosperafenib, and which of those have an active Phase 3 trial?

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