Limnetrelvir

DB21677ExperimentalSmall molecule

Limnetrelvir is a small molecule drug. The usage of the INN stem '-trelvir' in the name indicates that Limnetrelvir is a antiviral 3CL protease inhibitor. Limnetrelvir has a monoisotopic molecular...

Mechanism: Pharmacologically active on Replicase polyprotein 1ab
Curator reviewed
Formula / weight: C₂₇H₂₃F₄N₅O₄ · 557.506 g/mol (avg)

Resolves to

Compound

UNII4TPS988XGGCAS2923500-04-1ChEMBLCHEMBL6103371

Structure

InChIKeyKPYQLMJUGSDJQX-MRXNPFEDSA-NSMILESFC1=C2NC(=O)C=C(C(=O)N[C@@H]3CCN(C3)C3=C(C=C(C=C3C(F)(F)F)C#N)C(=O)N3CCOCC3)C2=CC=C1

Targets

P0DTD1rep

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Limnetrelvir, and which of those have an active Phase 3 trial?

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