Vicadrostat

DB21693InvestigationalSmall molecule

Vicadrostat is a small molecule drug. The usage of the INN stem '-drostat' in the name indicates that Vicadrostat is a inhibitor of the synthesis of aldosterone and cortisol. Vicadrostat... Vicadrostat is under investigation in clinical trial NCT07064473 (A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease).

Mechanism: Pharmacologically active on Cytochrome P450 11B2, mitochondrial
Curator reviewed
Formula / weight: C₁₅H₁₂ClN₃O₃ · 317.73 g/mol (avg)
Code names: BI 690517

Resolves to

Compound

UNIIAF4VW4GA3HCAS1868065-21-7ChEMBLCHEMBL6068035

Structure

InChIKeyMCVIVPZYYMNCAW-OAHLLOKOSA-NSMILESC[C@]1(CO)CC2=C(N(C=N2)C2=CC(Cl)=C(C=C2)C#N)C(=O)O1

Targets

P19099CYP11B2

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

8Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Vicadrostat, and which of those have an active Phase 3 trial?

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