Gozetotide

DB21811ApprovedInvestigationalSmall molecule

Gozetotide: Overview.

Mechanism: Pharmacologically active on Glutamate carboxypeptidase 2
Curator reviewed
Formula / weight: C₄₄H₆₂N₆O₁₇ · 947.005 g/mol (avg)
First approval: United States, 2021 · European Union, 2023
Code names: DKFZ-PSMA-11 · PSMA-11
Brand names: Locametz

Resolves to

Compound

Clinical / RWD

Structure

OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)CCCCCNC(=O)CCC1=CC=C(O)C(CN(CCN(CC(O)=O)CC2=CC(CCC(O)=O)=CC=C2O)CC(O)=O)=C1)C(O)=O)C(O)=O

Targets

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

48Clinical trialsPhase, status and sponsor resolved per trial

5Marketed productsAcross 2 countries and 5 labellers

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Gozetotide, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.