177Lu-PSMA-I&T

DB22176InvestigationalSmall molecule

177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).

Mechanism: Pharmacologically active on Glutamate carboxypeptidase 2
Curator reviewed
Also known as: [177Lu]Lu-PSMA I&T · [177Lu]Lu-PSMAI&T · [Lu-177]-PNT2002 · 177Lu-PNT2002 · 177Lu-PSMA I&T

Resolves to

Compound

UNIIG5B860B0G1

Targets

Q04609FOLH1

What you can answer from here — as of June 26, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

16Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with 177Lu-PSMA-I&T, and which of those have an active Phase 3 trial?

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