AR-12

DB33575InvestigationalSmall molecule

AR-12: Overview.

Chemical structure of AR-12
Formula / weight
C26H19F3N4O · 460.46 g/mol (avg)
Also known as
Pdk1 inhibitor ar-12
Code names
AR-12 · OSU-03012

Resolves to

Compound
UNIIEX3O2Q61UVCAS742112-33-0ChEMBLCHEMBL1650595ChEBI131196PubChem10027278
Structure
InChIKeyYULUCECVQOCQFQ-UHFFFAOYSA-NSMILESNCC(=O)NC1=CC=C(C=C1)N1N=C(C=C1C1=CC2=C(C=C1)C1=C(C=CC=C1)C=C2)C(F)(F)F
Targets
O15530PDPK1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with AR-12, and which of those have an active Phase 3 trial?

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