PLX-5622

DB33604InvestigationalSmall molecule

PLX-5622: Overview.

Mechanism: Pharmacologically active on Macrophage colony-stimulating factor 1 receptor
Curator reviewed
Formula / weight: C₂₁H₁₉F₂N₅O · 395.414 g/mol (avg)
Code names: PLX-5622

Resolves to

Compound

Structure

InChIKeyNSMOZFXKTHCPTQ-UHFFFAOYSA-NSMILESCOC1=C(CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C34)C=C2)C=C(F)C=N1

Targets

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with PLX-5622, and which of those have an active Phase 3 trial?

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