NGD-8243

DB33643InvestigationalSmall molecule

NGD-8243: Overview.

Chemical structure of NGD-8243
Formula / weight
C21H12F6N4 · 434.345 g/mol (avg)
Code names
MK-2295 · MK-2295-005 · NGD-8243

Resolves to

Compound
UNIIK3S4K8ACHECAS573678-04-3ChEMBLCHEMBL214796ChEBI748753PubChem11247522
Structure
InChIKeyVTANGSDRFFLTSQ-UHFFFAOYSA-NSMILESFC(F)(F)C1=CC=C(NC2=NC=NC3=CC(=CC=C23)C2=C(C=CC=N2)C(F)(F)F)C=C1
Targets
Q8NER1TRPV1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with NGD-8243, and which of those have an active Phase 3 trial?

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