Advanced uterine sarcoma

Drugs
Drugs and Targets

Drug	Drug Name	Drug Description
DB00997	Doxorubicin	A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.

Drug	Drug Name	Target	Type
DB00997	Doxorubicin	DNA topoisomerase 2-alpha	target
DB00997	Doxorubicin	DNA	target
DB00997	Doxorubicin	Cytochrome P450 3A4	enzyme
DB00997	Doxorubicin	Cytochrome P450 2D6	enzyme
DB00997	Doxorubicin	Cytochrome P450 2B6	enzyme
DB00997	Doxorubicin	P-glycoprotein 1	transporter
DB00997	Doxorubicin	Canalicular multispecific organic anion transporter 2	transporter
DB00997	Doxorubicin	Multidrug resistance-associated protein 6	transporter
DB00997	Doxorubicin	Multidrug resistance-associated protein 1	transporter
DB00997	Doxorubicin	Multidrug resistance-associated protein 7	transporter
DB00997	Doxorubicin	ATP-binding cassette sub-family G member 2	transporter
DB00997	Doxorubicin	Bile salt export pump	transporter
DB00997	Doxorubicin	Solute carrier family 22 member 16	transporter
DB00997	Doxorubicin	ATP-binding cassette sub-family B member 8, mitochondrial	transporter
DB00997	Doxorubicin	Cytochrome P450 1B1	enzyme
DB00997	Doxorubicin	Carbonyl reductase [NADPH] 1	enzyme
DB00997	Doxorubicin	Carbonyl reductase [NADPH] 3	enzyme
DB00997	Doxorubicin	Alcohol dehydrogenase [NADP(+)]	enzyme
DB00997	Doxorubicin	Aldo-keto reductase family 1 member C3	enzyme
DB00997	Doxorubicin	NAD(P)H dehydrogenase [quinone] 1	enzyme
DB00997	Doxorubicin	Xanthine dehydrogenase/oxidase	enzyme
DB00997	Doxorubicin	Nitric oxide synthase, endothelial	enzyme
DB00997	Doxorubicin	Nitric oxide synthase, inducible	enzyme
DB00997	Doxorubicin	Nitric oxide synthase, brain	enzyme
DB00997	Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	enzyme
DB00997	Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	enzyme
DB00997	Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	enzyme
DB00997	Doxorubicin	NADPH--cytochrome P450 reductase	enzyme
DB00997	Doxorubicin	RalA-binding protein 1	transporter
DB00997	Doxorubicin	Canalicular multispecific organic anion transporter 1	transporter
DB00997	Doxorubicin	Serum albumin	carrier
DB00997	Doxorubicin	Nucleolar and coiled-body phosphoprotein 1	target
DB00997	Doxorubicin	DNA topoisomerase 1	target
DB00997	Doxorubicin	DNA topoisomerase 2-beta	target
DB00997	Doxorubicin	Aldose reductase	enzyme
DB00997	Doxorubicin	Aldo-keto reductase family 1 member B10	enzyme
DB00997	Doxorubicin	Aldo-keto reductase family 1 member C4	enzyme

Drug	Drug Name	Phase	Status	Count