Type One Diabetes Completed Phase 1 Trials for Glucagon (DB00040)

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Also known as: Diabetes Mellitus, Juvenile-Onset / T1DM - Type 1 Diabetes Mellitus / Diabetes Type I / Type I Diabetes / Type1 Diabetes / Diabetes Type One / Diabete Type 1 / Type One Diabetes Mellitus / Diabetics Mellitus Type 1 / Type 1 Diabetes / Type 1 Diabetes Mellitus (T1DM) / Insulin-Dependent Diabetes Mellitus 1 / Type1diabetes / Diabetes Mellitus Type I / Type1 Diabetes Mellitus / Type 1 Diabetes (T1D) / Diabetes Mellitus Type 1 / Juvenile Onset Diabetes Mellitus / Diabetes Type 1 / Type 1 Insulin-Dependent Diabetes Mellitus / Type I Diabetes Mellitus / Diabetes Mellitus, Sudden-Onset / Type-1 Diabetes Mellitus / Insulin Dependent Diabetes Mellitus 1 / Type 1 Diabetes Mellitus / Juvenile-Onset Diabetes / Diabetes Mellitus, Insulin-Dependent, 1 / Diabetes mellitus type 1 (disorder) / Diabetes mellitus: [juvenile] or [insulin dependent] / Juvenile diabetes / Insulin dependent diabetic / IDDM / Diabetes mellitus insulin-dependent / Insulin-dependent diabetes mellitus / Diabetes mellitus juvenile onset / Immune-mediated diabetes / Insulin dependent diabetes mellitus / Insulin dependent diabetes mel / IDDM - Insulin-dependent diabetes mellitus / Diabetes mellitus - juvenile / Ketosis-prone diabetes mellitus (disorder) / Ketosis-prone diabetes mellitus

Indication	Status	Phase
DBCOND0076728 (Type One Diabetes)	Completed	1

clinicaltrials.gov Identifier	Title	Purpose	Drugs
NCT04992312	A Study of Nasal Glucagon (LY900018) in Pediatric Participants With Type 1 Diabetes	Basic Science	Glucagon (DB00040)
NCT03424044	Three Way Crossover Closed Loop Study With Xeris Glucagon	Treatment	Glucagon (DB00040)
NCT02910518	A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus	Treatment	Dextrose, unspecified form (DB09341) Glucagon (DB00040) Heparin (DB01109) Insulin aspart (DB01306) Insulin glulisine (DB01309) Insulin human (DB00030)
NCT06588504	Research Study in Japan to Compare Dasiglucagon With Glucagon in Treating Very Low Levels of Blood Sugar in Asian Adults With Type 1 Diabetes and Testing of Dasiglucagon for the Same Condition in Japanese Adolescents	Treatment	Dasiglucagon (DB15226) Glucagon (DB00040)
NCT02806973	A Study of Single or Repeated Doses of Glucagon in Participants With Diabetes	Basic Science	Glucagon (DB00040)
NCT01916265	Trial to Compare the Relative Pharmacodynamic Properties of Different Glucagon Dosages	Basic Science	Glucagon (DB00040)
NCT02625636	A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Doses of SAR438544 in Comparison to Placebo and Glucagon in Healthy Subjects and Type 1 Diabetes Mellitus Patients	Basic Science	Glucagon (DB00040)
NCT03176524	A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM	Treatment	Glucagon (DB00040)
NCT03444467	First Research Study to Compare a Possible New Medicine NNC9204-1513 to the Medicine Glucagon, in Healthy People.	Treatment	Glucagon (DB00040)
NCT03339453	A Study of Nasal Glucagon in Participants With Type 1 Diabetes Mellitus	Basic Science	Glucagon (DB00040)
NCT01640834	Study of LY2409021 in Participants With Type 1 Diabetes	Treatment	Adomeglivant (DB11704) Glucagon (DB00040)
NCT00304538	A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus	Treatment	Glucagon (DB00040)