Pharmaco-transcriptomicsUp/down regulation of genes due to the metabolism of pharmaceutical compounds

Pharmaco-genomics Pharmaco-metabolomics Pharmaco-transcriptomics Pharmaco-proteomics Search

Displaying entries 75926 - 75950 of 102031 in total

Drug	Drug Groups	Gene	Gene ID	Change	Interaction	Chromosome	References
							Clear
Somatostatin	Approved Investigational Withdrawn	SSTR5	6755	upregulated	Somatostatin results in increased expression of SSTR5 mRNA	16p13.3	A24325
Sorafenib	Approved Investigational	ATF4	468	upregulated	sorafenib results in increased expression of ATF4 mRNA	22q13.1	A24326
Sorafenib	Approved Investigational	BCL2	596	downregulated	sorafenib results in decreased expression of BCL2 mRNA	18q21.33	A21790
Sorafenib	Approved Investigational	BIRC5	332	downregulated	sorafenib results in decreased expression of BIRC5 mRNA	17q25.3	A21790
Sorafenib	Approved Investigational	CCND1	595	downregulated	sorafenib results in decreased expression of CCND1 mRNA	11q13.3	A24327
Sorafenib	Approved Investigational	CDK2	1017	downregulated	sorafenib results in decreased expression of CDK2 mRNA	12q13.2	A21790
Sorafenib	Approved Investigational	CDK9	1025	downregulated	sorafenib results in decreased expression of CDK9 mRNA	9q34.11	A21790
Sorafenib	Approved Investigational	CYLD	1540	upregulated	sorafenib results in increased expression of CYLD mRNA	16q12.1	A24328
Sorafenib	Approved Investigational	DDIT3	1649	upregulated	[sorafenib results in increased expression of ATF4 protein] which results in increased expression of DDIT3 mRNA	12q13.3	A24326
Sorafenib	Approved Investigational	DDIT3	1649	upregulated	sorafenib results in increased expression of DDIT3 mRNA	12q13.3	A24326
Sorafenib	Approved Investigational	EGFR	1956	downregulated	sorafenib results in decreased expression of EGFR mRNA	7p11.2	A21790
Sorafenib	Approved Investigational	GADD45B	4616	upregulated	sorafenib results in increased expression of GADD45B mRNA	19p13.3	A24329
Sorafenib	Approved Investigational	GADD45G	10912	upregulated	sorafenib results in increased expression of GADD45G mRNA	9q22.2	A24330
Sorafenib	Approved Investigational	GRB2	2885	downregulated	sorafenib results in decreased expression of GRB2 mRNA	17q25.1	A21790
Sorafenib	Approved Investigational	HDAC6	10013	downregulated	sorafenib results in decreased expression of HDAC6 mRNA	Xp11.23	A21790
Sorafenib	Approved Investigational	HIF1A	3091	downregulated	sorafenib results in decreased expression of HIF1A mRNA	14q23.2	A21790
Sorafenib	Approved Investigational	IGF1R	3480	downregulated	sorafenib results in decreased expression of IGF1R mRNA	15q26.3	A21790
Sorafenib	Approved Investigational	IRF5	3663	upregulated	sorafenib results in increased expression of IRF5 mRNA	7q32.1	A21790
Sorafenib	Approved Investigational	JUN	3725	upregulated	sorafenib results in increased expression of JUN mRNA	1p32.1	A24329
Sorafenib	Approved Investigational	MDM2	4193	upregulated	sorafenib results in increased expression of MDM2 mRNA	12q15	A21790
Sorafenib	Approved Investigational	MTOR	2475	downregulated	sorafenib results in decreased expression of MTOR mRNA	1p36.22	A21790
Sorafenib	Approved Investigational	NRAS	4893	downregulated	sorafenib results in decreased expression of NRAS mRNA	1p13.2	A21790
Sorafenib	Approved Investigational	PIK3C2A	5286	downregulated	sorafenib results in decreased expression of PIK3C2A mRNA	11p15.1	A21790
Sorafenib	Approved Investigational	PIK3CA	5290	downregulated	sorafenib results in decreased expression of PIK3CA mRNA	3q26.32	A21790
Sorafenib	Approved Investigational	PLK2	10769	upregulated	sorafenib results in increased expression of PLK2 mRNA	5q11.2	A21790

Displaying entries 75926 - 75950 of 102031 in total

Pharmaco-transcriptomicsUp/down regulation of genes due to the metabolism of pharmaceutical compounds

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