| Carvedilol | Approved Investigational | HMOX1 | 3162 |
upregulated | carvedilol results in increased expression of HMOX1 mRNA | 22q12.3 | |
| Carvedilol | Approved Investigational | TGFB1 | 7040 |
downregulated | carvedilol results in decreased expression of TGFB1 mRNA | 19q13.1 | |
| Custirsen | Investigational | ACAP2 | 23527 |
upregulated | CC-8490 results in increased expression of ACAP2 mRNA | 3q29 | |
| Custirsen | Investigational | ACTR1B | 10120 |
downregulated | CC-8490 results in decreased expression of ACTR1B mRNA | 2q11.2 | |
| Custirsen | Investigational | ATF3 | 467 |
upregulated | CC-8490 results in increased expression of ATF3 mRNA | 1q32.3 | |
| Custirsen | Investigational | BCL6 | 604 |
upregulated | CC-8490 results in increased expression of BCL6 mRNA | 3q27.3 | |
| Custirsen | Investigational | CDK1 | 983 |
downregulated | CC-8490 results in decreased expression of CDK1 mRNA | 10q21.2 | |
| Custirsen | Investigational | CEBPB | 1051 |
upregulated | CC-8490 results in increased expression of CEBPB mRNA | 20q13.13 | |
| Custirsen | Investigational | CTBS | 1486 |
upregulated | CC-8490 results in increased expression of CTBS mRNA | 1p22.3 | |
| Custirsen | Investigational | CXCL8 | 3576 |
upregulated | CC-8490 results in increased expression of CXCL8 mRNA | 4q13.3 | |
| Custirsen | Investigational | DAG1 | 1605 |
upregulated | CC-8490 results in increased expression of DAG1 mRNA | 3p21.31 | |
| Custirsen | Investigational | DDIT3 | 1649 |
upregulated | CC-8490 results in increased expression of DDIT3 mRNA | 12q13.3 | |
| Custirsen | Investigational | DDX42 | 11325 |
upregulated | CC-8490 results in increased expression of DDX42 mRNA | 17q23.3 | |
| Custirsen | Investigational | DUSP5 | 1847 |
upregulated | CC-8490 results in increased expression of DUSP5 mRNA | 10q25.2 | |
| Custirsen | Investigational | EIF5 | 1983 |
upregulated | CC-8490 results in increased expression of EIF5 mRNA | 14q32.32 | |
| Custirsen | Investigational | GADD45A | 1647 |
upregulated | CC-8490 results in increased expression of GADD45A mRNA | 1p31.3 | |
| Custirsen | Investigational | GFPT1 | 2673 |
upregulated | CC-8490 results in increased expression of GFPT1 mRNA | 2p13.3 | |
| Custirsen | Investigational | IER3 | 8870 |
upregulated | CC-8490 results in increased expression of IER3 mRNA | 6p21.33 | |
| Custirsen | Investigational | IL6 | 3569 |
upregulated | CC-8490 results in increased expression of IL6 mRNA | 7p15.3 | |
| Custirsen | Investigational | KYNU | 8942 |
upregulated | CC-8490 results in increased expression of KYNU mRNA | 2q22.2 | |
| Custirsen | Investigational | LARP6 | 55323 |
upregulated | CC-8490 results in increased expression of LARP6 mRNA | 15q23 | |
| Custirsen | Investigational | MCM7 | 4176 |
downregulated | CC-8490 results in decreased expression of MCM7 mRNA | 7q22.1 | |
| Custirsen | Investigational | NFKB1 | 4790 |
upregulated | CC-8490 results in increased expression of NFKB1 mRNA | 4q24 | |
| Custirsen | Investigational | PCLAF | 9768 |
downregulated | CC-8490 results in decreased expression of PCLAF mRNA | 15q22.31 | |
| Custirsen | Investigational | PGGT1B | 5229 |
upregulated | CC-8490 results in increased expression of PGGT1B mRNA | 5q22.3 | |