Reaction: Irinotecan to 1 product

hydrolysisMajor circulating metaboliteMetabolism of Irinotecan

Irinotecan is converted to SN-38 by Human Carboxylesterases.

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What you can answer from here — as of March 25, 2024

1EnzymeEach linked to its target card
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3ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Human Carboxylesterases, and which of those pairings are clinically significant?

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