Reaction: Alectinib to 1 product
- Reaction
- Reaction type
- Not Available
- Direction
- Not Available
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- active
- References
- Sato-Nakai M, Kawashima K, Nakagawa T, Tachibana Y, Yoshida M, Takanashi K, Morcos PN, Binder M, Moore DJ, Yu L: Metabolites of alectinib in human: their identification and pharmacological activity. Heliyon. 2017 Jul 10;3(7):e00354. doi: 10.1016/j.heliyon.2017.e00354. eCollection 2017 Jul. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 3A4 Not Available Not Available confirmed