Reaction: Alectinib to 1 product

Reaction
Reaction type
Not Available
Direction
Not Available
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Sato-Nakai M, Kawashima K, Nakagawa T, Tachibana Y, Yoshida M, Takanashi K, Morcos PN, Binder M, Moore DJ, Yu L: Metabolites of alectinib in human: their identification and pharmacological activity. Heliyon. 2017 Jul 10;3(7):e00354. doi: 10.1016/j.heliyon.2017.e00354. eCollection 2017 Jul. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableconfirmed