Reaction: Saquinavir to 1 product

Aliphatic hydroxylationMetabolism of Saquinavir

Saquinavir is converted to (2S)-N-[(2S,3R)-4-[(3S,4aR,8aS)-3-(tert-butylcarbamoyl)-6-hydroxy-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-[(quinolin-2-yl)formamido]butanediamide by Cytochrome P450 3A4.

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What you can answer from here — as of October 27, 2017

1EnzymeEach linked to its target card
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Which other drugs are metabolised by Cytochrome P450 3A4, and which of those pairings are clinically significant?

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