Reaction: Ibrutinib to 1 product

Ring epoxidation; hydrolysisMajor circulating metaboliteMetabolism of Ibrutinib

Ibrutinib is converted to PCI-45227 (M37).

Reaction
Ibrutinib
DB09053
    PCI-45227 (M37)
    DBMET02022
    Direction
    Activity
    active

    What you can answer from here — as of March 29, 2018

    1ReferenceThe literature this reaction is curated from
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    Which metabolites of Ibrutinib are active, and how do they change its interactions?

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