Reaction: Ropivacaine to 1 product

Reaction
Ropivacaine
DB00296
3-hydroxyropivacaine
DBMET00269
Reaction type
3-hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Halldin MM, Bredberg E, Angelin B, Arvidsson T, Askemark Y, Elofsson S, Widman M: Metabolism and excretion of ropivacaine in humans. Drug Metab Dispos. 1996 Sep;24(9):962-8. [Article]
  2. FDA Approved Drug Products: Naropin (ropivacaine hydrochloride) for injection (2022) [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 1A2Not AvailableNot Availableimplied